SMARTEEN™, a distinctive natural active ingredient, is artfully crafted to shape a vision of timeless beauty. Extracted from the
roots of Butcher’s Broom, this pure blend of neoruscogenin and ruscogenin undergoes a refined purification process, reminiscent
of an artistic creation.

This natural active ingredient focuses on reducing eye bags by enhancing microcirculation, diminishes dark circles and brown
spots through its anti-tyrosinase effect, and smooths wrinkles and crow’s feet by boosting collagen type I production.
Additionally, it effectively reduces redness and inflammation, providing instant efficacy through the modulation of IL-6 levels.

SMARTEEN™ now stands as an essential cornerstone in the field of neurocosmetics, addressing physiological challenges primarily
induced by stress. With its sophisticated blend and profound understanding of skin-brain communication, SMARTEEN™ is not just
a skincare solution but a masterpiece in the art of promoting beauty and well-being.

Why You Will Love It?

• Provides a soothing effect

• Enhances microcirculation by mimicking norephinephrine

• Acts on the IL-6 cytokine at the cellular level to reduces redness

• Promotes well-aging through demonstrated anti-wrinkle efficacy

• Treats dark spots, dark circles, and post-inflammatory hyperpigmentation by inhibiting tyrosinase

• Demonstrates a reduction in eye bags through a vasoconstrictive effect, achieved by both increasing norepinephrine release and directly binding to postjunctional alpha-adrenergic receptors, thus mimicking its action

• Boosts the collagen type I production

• Provides instant efficacy at the clinical level

• Extracted as pure molecule from butcher’s broom roots, serves as a premium active ingredient

• Multifunctional neurobeauty

SMARTEEN™ is a pure blend of neoruscogenin and ruscogenin that undergoes a refined purification process that is extracted from the roots of Butcher ‘ s Broom. It is a great active for the neurocosmetics field since it is directly effective on cutaneous nervous fiber endings, triggering and/or mimicking neurotransmitter release, thereby eliminating the physiological consequences that occur on the skin at the cosmetic level.

SMARTEEN™ , with documented anti-elastase activity, is known to improve microcirculation with vasoconstrictive effect by both increasing the release of norepinephrine and directly binding to postjunctional alpha-adrenergic receptors by mimicking its action, was tested on volunteers through clinical study against eye bags. After using the eye serum containing 0.1% SMARTEEN™ , 50% of the volunteers noticed a visible change in their eye bags within the first 5 minutes. This resulted in an enhanced sense of well-being and increased self-confidence, indicating instant efficacy.

SMARTEEN™ shows anti-dark circle effect by capability to inhibit the tyrosinase enzyme at the cellular level. SMARTEEN™ has been demonstrated to prevent hyperpigmentation by inhibiting the tyrosinase enzyme, consequently reducing the heightened tyrosinase activity induced by stress and lack of sleep. This functionality positions SMARTEEN™ as a potential solution to significant issues such as dark circles under the eyes.

SMARTEEN™ inhibits the release of the IL-6 cytokine in the presence of an inflammation-inducing factor, TNF-α. Upon topical application, it demonstrates an anti-redness effect, showing efficacy in reducing red areas and alleviating erythema.

SMARTEEN™ acts on wrinkles and crow ‘ s feet caused by stress-induced collagen deficiency in the eye contour area. It Increases collagen type I synthesis by upregulating COL1A1 gene expression and offers well-aged skin.

Neoruscogenin, Ruscogenin

• Face Cream
• Eye Contour Cream
• BB & CC Cream
• Face Serum
• Eye Contour Serum
• Concealer & Foundation

Soothing

Microcirculation Enhancer

Anti-Redness

 Reduction in Wrinkles

 Tyrosinase Inhibition

 Eye Bags Reduction

 Enhancement of Collagen Levels

 Neurocosmetic Active