AST-4™

Longevity-Driven Cellular Programming

AST-4 BEFORE AST-4 AFTER

Derived from Astragalus membranaceus and enriched in Astragaloside IV, AST-4™ is built on a saponin-based molecular system that combines natural origin with targeted biological precision.

Instead of focusing on a single pathway, AST-4™ supports coordinated cellular performance. It helps the skin adapt, respond, and maintain its functionality over time by reinforcing cellular resilience.

Developed through computational bioactivity mapping and supported by a combination of in silico modeling, targeted in vitro validation, and clinical evaluation at both 1 hour and 28 days, AST-4™ works across interconnected mechanisms associated with skin longevity. It contributes to maintaining balance under stress conditions while supporting renewal dynamics, structural integrity, and resilience at the cellular level. This approach translates molecular-level activity into visible skin outcomes, linking immediate effects with long-term skin performance.

This multi-dimensional approach enables both immediate visible results and long-term skin performance support.

HIGHLIGHTS

Skin Longevity Support

Supports senescence modulation and autophagic balance for sustained skin longevity

Skin Firming and Anti-sagging Effect

Supports elasticity and a more lifted skin appearance with +166% ECM remodeling 

Nasolabial Fold Wrinkle Reduction of 10.04% (28 days vs placebo)

Visibly improves the appearance of deep wrinkles in the mid-face area

 

8.56% Reduction in Crow’s Feet Wrinkles (28 days vs placebo)

Helps smooth fine lines around the eye contour

18.09% Instant Glow in 1 Hour

Visible radiance and revitalized appearance within just 60 minutes

Molecular Signature: Astragaloside IV

Standardized botanical system for targeted and consistent activity

CHARACTERISTICS

INCI

Astragalus membranaceus Root Extract, Maltodextrin

Recommended Use Level

0.1% to 0.5%

AST-4™

Longevity-Driven Cellular Programming skip render: ucaddon_uc_before_after Derived from Astragalus membranaceus and enriched in Astragaloside IV, AST-4™ is built on a saponin-based molecular system that combines natural origin with targeted biological precision. Instead of focusing on a single pathway, AST-4™ supports coordinated cellular performance. It helps the skin adapt, respond, and maintain its functionality over time […]